Product Name: D-Fructose 1,6-bisphosphate trisodium salt
Molecular Formula: C6H15NaO12P2
Molecular Weight: 364.11
Appearance: White to Off-white powder
Purity: 99%
CAS NO.: 38099-82-0
EINECS No.: 253-778-0
Supplier: ZHENYIBIO

Fructose-1,6-biphosphate (F1,6P) is a glycolytic intermediate produced by the transfer of a phosphate from ATP to fructose-6-phosphate by the enzyme phosphofructokinase. Fructose-1,6-biphosphate, along with fructose-2,6-biphosphate, modulates the activity of phosphofructokinase-1 (PFK-1), the rate-limiting step in glycolysis. During glycolysis, aldolase splits Fructose-1,6-biphosphate into dihydroxacetone phosphate (DHAP) and glyceraldehyde phosphate. Fructose-1,6-biphosphate is also an allosteric activator of the M2 isoform of Pyruvate Kinase (PK-M2), the predominant form of pyruvate kinase in cancer cells.